Tos-PEG2-Boc
Based on 1 Customer Validation
Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 1309666-78-1
- Formel: C16H24O6S
- Molecular Weight:344.42
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1309666-78-1
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Appearance Solid
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Molecular Weight 344.42
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Formel C16H24O6S
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)CCOCCOS(=O)(C1=CC=C(C)C=C1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (290.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9034 mL | 14.5172 mL | 29.0343 mL | 72.5858 mL |
| 5 mM | 0.5807 mL | 2.9034 mL | 5.8069 mL | 14.5172 mL | |
| 10 mM | 0.2903 mL | 1.4517 mL | 2.9034 mL | 7.2586 mL | |
| 15 mM | 0.1936 mL | 0.9678 mL | 1.9356 mL | 4.8391 mL | |
| 20 mM | 0.1452 mL | 0.7259 mL | 1.4517 mL | 3.6293 mL | |
| 25 mM | 0.1161 mL | 0.5807 mL | 1.1614 mL | 2.9034 mL | |
| 30 mM | 0.0968 mL | 0.4839 mL | 0.9678 mL | 2.4195 mL | |
| 40 mM | 0.0726 mL | 0.3629 mL | 0.7259 mL | 1.8146 mL | |
| 50 mM | 0.0581 mL | 0.2903 mL | 0.5807 mL | 1.4517 mL | |
| 60 mM | 0.0484 mL | 0.2420 mL | 0.4839 mL | 1.2098 mL | |
| 80 mM | 0.0363 mL | 0.1815 mL | 0.3629 mL | 0.9073 mL | |
| 100 mM | 0.0290 mL | 0.1452 mL | 0.2903 mL | 0.7259 mL |
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