TR79
TR79 is a mitochondrial ClpP protease activator with an EC50 of 414.49 nM. TR79 competitively occupies the ClpP binding site and attenuates MTP-B1-induced POLRMT degradation. TR79 can be used in research on mitochondria-related diseases (such as cancer and neurodegenerative diseases) and mitochondrial metabolic abnormalities.
For research use only. We do not sell to patients.
- CAS No.: 2365073-59-0
- Formula: C26H26F3N5O2
- Molecular Weight:497.51
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
TR79 is a potent ClpP agonist, with an EC50 of 414.49 nM in the ClpP activation assay[1].
TR79 competitively occupies the ClpP binding site and attenuates MTP-B1-induced POLRMT degradation in cultured cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS No. 2365073-59-0
-
Molecular Weight 497.51
-
Formula C26H26F3N5O2
-
SMILES
NCCCN(C1=C(CN(CC2=CC=CC(C#N)=C2)CC1)C(N3CC4=CC=C(C(F)(F)F)C=C4)=O)C3=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TR79 Related Classifications
HY-189815 Related Classifications
Powered by Bioz