trans-2-Pentenoic acid
Based on 1 Customer Validation
(2E)-Pent-2-enoic acid is an unsaturated carboxylic acid, it is also known as 2-pentenoic acid or crotonic acid, the "2E" designation indicates that the molecule has a trans double bond configuration, where the double bond The two carbon atoms on both sides are located on opposite sides, (2E)-Pent-2-enoic acid has a pungent odor, is miscible with water and most organic solvents, it is commonly used in organic synthesis as a variety of chemical reactions, including esterification, oxidation, and reduction, and in addition, its potential use as a flavoring agent in the food industry was investigated.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 13991-37-2
- Formula: C5H8O2
- Molecular Weight:100.12
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
(2E)-pent-2-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13991-37-2
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Appearance Liquid (Density: 0.99 g/cm3)
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Molecular Weight 100.12
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Formula C5H8O2
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Color Colorless to light yellow
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SMILES
CC\C=C\C(O)=O
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Synonyms
(E)-Pent-2-enoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (1997.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (49.94 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (243 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.9880 mL | 49.9401 mL | 99.8801 mL | 249.7004 mL |
| 5 mM | 1.9976 mL | 9.9880 mL | 19.9760 mL | 49.9401 mL | |
| 10 mM | 0.9988 mL | 4.9940 mL | 9.9880 mL | 24.9700 mL | |
| 15 mM | 0.6659 mL | 3.3293 mL | 6.6587 mL | 16.6467 mL | |
| 20 mM | 0.4994 mL | 2.4970 mL | 4.9940 mL | 12.4850 mL | |
| 25 mM | 0.3995 mL | 1.9976 mL | 3.9952 mL | 9.9880 mL | |
| 30 mM | 0.3329 mL | 1.6647 mL | 3.3293 mL | 8.3233 mL | |
| 40 mM | 0.2497 mL | 1.2485 mL | 2.4970 mL | 6.2425 mL | |
| 50 mM | 0.1998 mL | 0.9988 mL | 1.9976 mL | 4.9940 mL | |
| 60 mM | 0.1665 mL | 0.8323 mL | 1.6647 mL | 4.1617 mL | |
| 80 mM | 0.1249 mL | 0.6243 mL | 1.2485 mL | 3.1213 mL | |
| 100 mM | 0.0999 mL | 0.4994 mL | 0.9988 mL | 2.4970 mL |