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  2. nAChR Environmental Pollutants
  3. Triflumezopyrim

Triflumezopyrim, a mesoionic insecticide, has high efficiency at a low dosage, and is mainly used to control hopper species. Triflumezopyrim mainly acts on the nicotinic acetylcholine receptor (nAChR) inhibition, which is very highly efficient, rapidly effective, and nearly nontoxic to nontarget arthropods.

For research use only. We do not sell to patients.

Triflumezopyrim

Triflumezopyrim Chemical Structure

CAS No. : 1263133-33-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Triflumezopyrim, a mesoionic insecticide, has high efficiency at a low dosage, and is mainly used to control hopper species. Triflumezopyrim mainly acts on the nicotinic acetylcholine receptor (nAChR) inhibition, which is very highly efficient, rapidly effective, and nearly nontoxic to nontarget arthropods[1].

In Vitro

Triflumezopyrim (25 g a.i. ha−1) is effective for controllingbrown planthoppers (BPHs) 7-10 days after application in rice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Triflumezopyrim (0-10 mg/kg, mixed into 500 g of artificial soil) induces oxidative stress and DNA damage in earthworms[2].
Triflumezopyrim (120 μg/mL, fed on sugar water, 72 h) has no high mortality effect on ants, but achieved 100% mortality at 10 μg/mL for 2 wk, indicating Triflumezopyrim is a slow acting toxin for managing red imported fire ants[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

398.34

Formula

C20H13F3N4O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N(CC2=CN=CN=C2)C3=CC=CC=[N+]3C([O-])=C1C4=CC(C(F)(F)F)=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (251.04 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5104 mL 12.5521 mL 25.1042 mL
5 mM 0.5021 mL 2.5104 mL 5.0208 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.48%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5104 mL 12.5521 mL 25.1042 mL 62.7605 mL
5 mM 0.5021 mL 2.5104 mL 5.0208 mL 12.5521 mL
10 mM 0.2510 mL 1.2552 mL 2.5104 mL 6.2760 mL
15 mM 0.1674 mL 0.8368 mL 1.6736 mL 4.1840 mL
20 mM 0.1255 mL 0.6276 mL 1.2552 mL 3.1380 mL
25 mM 0.1004 mL 0.5021 mL 1.0042 mL 2.5104 mL
30 mM 0.0837 mL 0.4184 mL 0.8368 mL 2.0920 mL
40 mM 0.0628 mL 0.3138 mL 0.6276 mL 1.5690 mL
50 mM 0.0502 mL 0.2510 mL 0.5021 mL 1.2552 mL
60 mM 0.0418 mL 0.2092 mL 0.4184 mL 1.0460 mL
80 mM 0.0314 mL 0.1569 mL 0.3138 mL 0.7845 mL
100 mM 0.0251 mL 0.1255 mL 0.2510 mL 0.6276 mL
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Triflumezopyrim
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HY-145296
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