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  3. Triptolide palmitate

Triptolide palmitate is the derivative of Triptolide (HY-32735). Triptolide palmitate exhibits cytotoxicity against cancer cell MCF-7 and A549, with IC50 of 7.5 and 6.4 μM. Triptolide palmitate exhibits a half-time T1/2 of 50.4 min in Sprague Dawley rats. Triptolide palmitate can be utilizd as drug carrier.

For research use only. We do not sell to patients.

Triptolide palmitate Chemical Structure

Triptolide palmitate Chemical Structure

CAS No. : 2126920-51-0

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10 mg USD 350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Triptolide palmitate is the derivative of Triptolide (HY-32735). Triptolide palmitate exhibits cytotoxicity against cancer cell MCF-7 and A549, with IC50 of 7.5 and 6.4 μM. Triptolide palmitate exhibits a half-time T1/2 of 50.4 min in Sprague Dawley rats. Triptolide palmitate can be utilizd as drug carrier[1].

Molecular Weight

598.81

Formula

C36H54O7

CAS No.
Unlabeled CAS

Appearance

Oil

SMILES

C[C@@]12[C@@]34[C@@]5([C@@](C[C@@]1([H])C6=C(C(OC6)=O)CC2)([H])O5)[C@@H]([C@@]7([C@](O7)([H])[C@]3([H])O4)C(C)C)OC(CCCCCCCCCCCCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (167.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6700 mL 8.3499 mL 16.6998 mL
5 mM 0.3340 mL 1.6700 mL 3.3400 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6700 mL 8.3499 mL 16.6998 mL 41.7495 mL
5 mM 0.3340 mL 1.6700 mL 3.3400 mL 8.3499 mL
10 mM 0.1670 mL 0.8350 mL 1.6700 mL 4.1749 mL
15 mM 0.1113 mL 0.5567 mL 1.1133 mL 2.7833 mL
20 mM 0.0835 mL 0.4175 mL 0.8350 mL 2.0875 mL
25 mM 0.0668 mL 0.3340 mL 0.6680 mL 1.6700 mL
30 mM 0.0557 mL 0.2783 mL 0.5567 mL 1.3916 mL
40 mM 0.0417 mL 0.2087 mL 0.4175 mL 1.0437 mL
50 mM 0.0334 mL 0.1670 mL 0.3340 mL 0.8350 mL
60 mM 0.0278 mL 0.1392 mL 0.2783 mL 0.6958 mL
80 mM 0.0209 mL 0.1044 mL 0.2087 mL 0.5219 mL
100 mM 0.0167 mL 0.0835 mL 0.1670 mL 0.4175 mL
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Triptolide palmitate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Triptolide palmitate
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HY-158090
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