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Cat. No.: HY-115915

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TS010

TS010 is a potent inhibitor of GLO-I with IC₅₀ of 0.57 μM. TS010 has the potential for the research of cancer disease.

For research use only. We do not sell to patients.

Formula: C₁₆H₁₂N₄O₄S
Molecular Weight:356.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

TS010 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TS010 is a potent inhibitor of GLO-I with IC₅₀ of 0.57 μM. TS010 has the potential for the research of cancer disease^[1].

Chemical Information

Molecular Weight 356.36
Formula C₁₆H₁₂N₄O₄S
SMILES

[H]C(C1=NC2=C(C(/N=N/C3=CC=CC(S(N)(=O)=O)=C3)=CC=C2O)C=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Al-Oudat BA, et al. Lead optimization and biological evaluation of diazenylbenzenesulfonamides inhibitors against glyoxalase-I enzyme as potential anticancer agents [published online ahead of print, 2022 Feb 5]. Bioorg Chem. 2022;120:105657. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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