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Cat. No.: HY-D1685

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BZiPAR

Name: BZiPAR
Brand: MedChemExpress
SKU: HY-D1685
Price: 276.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease.

For research use only. We do not sell to patients.

Purity : 93%
CAS No.: 254451-46-2
Formula: C₇₀H₈₈Cl₂N₁₄O₁₃
Molecular Weight:1404.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BZiPAR Chemical Structure

CAS No.: 254451-46-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BZiPAR is a fluorescent probe. BZiPAR also is a substrate of trypsin that becomes fluorescent after cleavage by the protease^[1].

In Vitro

Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
Confocal Imaging of Trypsinogen Activation:
1. Incubate the cells according to your normal protocol.
2. Isolate clusters of acinar cells.
3. Incubate acini in extracellular solution containing 100 μM BZiPAR.
4. BZiPAR were excited with a 488-nm laser line; emission was collected in the 508- to 530-nm band for cleaved BZiPAR.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 254451-46-2
Appearance Solid
Molecular Weight 1404.44
Formula C₇₀H₈₈Cl₂N₁₄O₁₃
Color Off-white to yellow
SMILES

CC[C@@H](C)[C@H](NC(OCC1=CC=CC=C1)=O)C(N2[C@@H](CCC2)C(N[C@H](C(NC3=CC=C(C(C(C=CC=C4)=C4C5=O)(O5)C6=C7C=C(NC([C@@H](NC([C@@H]8CCCN8C([C@@H](NC(OCC9=CC=CC=C9)=O)[C@H](C)CC)=O)=O)CCCNC(N)=N)=O)C=C6)C(O7)=C3)=O)CCCNC(N)=N)=O)=O.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mark W Sherwood, et al. Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5674-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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