Chol-PEG
Chol-PEG is an amphiphilic cholesterol-polyethylene glycol conjugate and also a liposomelike surface modifier. After Chol-PEG is incorporated into liposomelike vesicles, it forms a hydrophilic barrier on their surface, increases the thickness of the bound water layer around the liposomelike vesicles, and enhances the release rate of encapsulated compounds. Chol-PEG can be used as a modifier to prepare nonionic surfactant vesicles (liposomelike vesicles) for drug delivery applications.
For research use only. We do not sell to patients.
- CAS No.: 27321-96-6
- Formula: C29H50O2
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chol-PEG can form Chol-PEGm, which is used to modify nimodipine (HY-B0265)-loaded vesicles. As the molecular weight of PEG increases, the vesicle size increases, zeta potential decreases, and FALT increases; the release rate of nimodipine increases with the increase in PEG molecular weight; among these, vesicles modified with Chol-PEG10,000 show the highest cumulative release within 24 h, reaching up to 43.86%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 27321-96-6
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Formula C29H50O2
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SMILES
OCCOC1CC2=CCC3C(C2(CC1)C)CCC4(C(C(CCCC(C)C)C)CCC34)C.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chol-PEG Related Classifications
HY-144007 Related Classifications
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