Cytochlor
Based on 1 Customer Validation
Cytochlor is an analog of Cytidine (HY-B0158), which can be used as a radiosensitizer and exhibits antitumor activity.
For research use only. We do not sell to patients.
- Purity : 95.05%
- CAS No.: 32387-56-7
- Formula: C9H12ClN3O4
- Molecular Weight:261.66
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Description
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 32387-56-7
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Appearance Solid
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Molecular Weight 261.66
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Formula C9H12ClN3O4
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Color Off-white to light yellow
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SMILES
O=C1N=C(C(Cl)=CN1[C@@H]2O[C@@H]([C@H](C2)O)CO)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (382.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8218 mL | 19.1088 mL | 38.2175 mL | 95.5438 mL |
| 5 mM | 0.7644 mL | 3.8218 mL | 7.6435 mL | 19.1088 mL | |
| 10 mM | 0.3822 mL | 1.9109 mL | 3.8218 mL | 9.5544 mL | |
| 15 mM | 0.2548 mL | 1.2739 mL | 2.5478 mL | 6.3696 mL | |
| 20 mM | 0.1911 mL | 0.9554 mL | 1.9109 mL | 4.7772 mL | |
| 25 mM | 0.1529 mL | 0.7644 mL | 1.5287 mL | 3.8218 mL | |
| 30 mM | 0.1274 mL | 0.6370 mL | 1.2739 mL | 3.1848 mL | |
| 40 mM | 0.0955 mL | 0.4777 mL | 0.9554 mL | 2.3886 mL | |
| 50 mM | 0.0764 mL | 0.3822 mL | 0.7644 mL | 1.9109 mL | |
| 60 mM | 0.0637 mL | 0.3185 mL | 0.6370 mL | 1.5924 mL | |
| 80 mM | 0.0478 mL | 0.2389 mL | 0.4777 mL | 1.1943 mL | |
| 100 mM | 0.0382 mL | 0.1911 mL | 0.3822 mL | 0.9554 mL |