MAC-5576
MAC-5576 is a SARS-CoV-2 3CL protease inhibitor, with an IC50 of 81 nM. MAC-5576 also inhibits 3CLpro (IC50=0.5 μM), HAV 3Cpro (IC50=0.5 μM), and thrombin (IC50=13 μM).
For research use only. We do not sell to patients.
- CAS No.: 219929-01-8
- Formula: C10H6ClNO2S
- Molecular Weight:239.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 219929-01-8
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Molecular Weight 239.68
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Formula C10H6ClNO2S
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SMILES
O=C(C1=CC=CS1)OC2=CC(Cl)=CN=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jan E Blanchard, et al. High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase. Chem Biol. 2004 Oct;11(10):1445-53. [Content Brief]
[2]. Sho Iketani, et al. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nat Commun. 2021 Apr 1;12(1):2016. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAC-5576 Related Classifications
HY-44484 Related Classifications
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