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Cat. No.: HY-130509S

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MTSSLMTSSL-¹⁵N

(Synonyms: Otmpmms-¹⁵N)

MTSSL-¹⁵N (Otmpmms-¹⁵N) is the ¹⁵N-labeled MTSSL (HY-130509). MTSSL (Otmpmms) is a highly reactive thiol-specific spin label that can be used to label thiol residues in proteins for the determination of protein structure and dynamics, as well as studies on protein-protein interactions. MTSSL serves as a nitroxide labeling reagent for cysteine residues in recombinant mouse prion protein (moPrP^C) mutants. MTSSL can be applied in studies of transmissible spongiform encephalopathies (prion diseases).

For research use only. We do not sell to patients.

CAS No.: 1404308-02-6
Formula: C₁₀H₁₈¹⁵NO₃S₂^*
Molecular Weight:265.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

MTSSLMTSSL-¹⁵N Chemical Structure

CAS No.: 1404308-02-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
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Bioz

Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1404308-02-6
Unlabeled Cas 81213-52-7
Molecular Weight 265.38
Formula C₁₀H₁₈¹⁵NO₃S₂^*
SMILES

[O][15N]1C(C)(C)C(CSS(=O)(C)=O)=CC1(C)C
Synonyms

Otmpmms-¹⁵N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Watanabe Y, et al., Identification of pH-sensitive regions in the mouse prion by the cysteine-scanning spin-labeling ESR technique. Biochem Biophys Res Commun. 2006 Nov 24;350(3):549-56. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MTSSLMTSSL-15N

Biological Activity

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MTSSLMTSSL-15N Related Classifications

HY-130509S Related Classifications

MTSSLMTSSL-¹⁵N

MTSSLMTSSL-¹⁵N Related Classifications