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Cat. No.: HY-N19119

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Vertixanthone

Vertixanthone is an antifungal agent, with MIC values of 3.125 μg/mL against Candida albicans CMCC 98001 and 12.5 μg/mL against Aspergillus niger R330. Vertixanthone can be used for the research of candida albicans infection, aspergillus niger infection.

For research use only. We do not sell to patients.

CAS No.: 120461-93-0
Formula: C₁₅H₁₀O₅
Molecular Weight:270.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Vertixanthone Chemical Structure

CAS No.: 120461-93-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Vertixanthone (0-50.0 μg/mL; 24-48 h) potently inhibits Candida albicans CMCC 98001 with an MIC of 3.125 μg/mL and inhibits Aspergillus niger R330 with an MIC of 12.5 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 120461-93-0
Molecular Weight 270.24
Formula C₁₅H₁₀O₅
SMILES

O=C(OC)C=1C=CC=C2OC=3C=CC=C(O)C3C(=O)C21
Structure Classification
- Others
Initial Source
- Microorganisms
Paraconionthyrium sp. YM 311593
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Signal Pathway Related

Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang RH, et al. Two new polyketides isolated from the endophytic fungus Phomopsis heveicola POH-zhi and its antifungal activity. J Asian Nat Prod Res. 2026 Apr 10:1-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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