Tyk2-IN-5 (Standard)
Tyk2-IN-5 (Standard) is the analytical standard of Tyk2-IN-5 (HY-111745). This product is intended for research and analytical applications. Tyk2-IN-5 (compound 6) is a potent, selective and orally active tyrosine Kinase 2 (Tyk2) inhibitor that acts on the JH2 structural domain. Tyk2-IN-5 shows a Ki value of 0.086 nM for Tyk2 JH2 and an IC50 value of 25 nM for IFNα. Tyk2-IN-5 efficiently inhibits the production of IFNγ in a pharmacodynamic rat model and is fully efficacious in a rat model of arthritis.
For research use only. We do not sell to patients.
- CAS No.: 1797432-62-2
- Formula: C21H19FN8O2
- Molecular Weight:434.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1797432-62-2
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Molecular Weight 434.43
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Formula C21H19FN8O2
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SMILES
O=C1C(NC2=NN3C(C(NC)=C2)=NC=C3C(N[C@H]4[C@@H](F)C4)=O)=CC=CN1C5=CC=CC=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyk2-IN-5 (Standard) Related Classifications
HY-111745R Related Classifications
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