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Cat. No.: HY-130367

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U-48520

U-48520 is an agonist for μ-opioid receptor with EC₅₀ of 1561 nM.

For research use only. We do not sell to patients.

CAS No.: 67579-11-7
Formula: C₁₆H₂₃ClN₂O
Molecular Weight:294.82

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

U-48520 Chemical Structure

CAS No.: 67579-11-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

U-48520 is an agonist for μ-opioid receptor with EC₅₀ of 1561 nM^[1].

IC₅₀ & Target

μ Opioid Receptor/MOR

1561 nM (EC₅₀)

All Opioid Receptor Isoforms :

Chemical Information

CAS No. 67579-11-7
Molecular Weight 294.82
Formula C₁₆H₂₃ClN₂O
SMILES

O=C(N([C@H]1[C@H](N(C)C)CCCC1)C)C2=CC=C(Cl)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Otte L, et al., Investigation of the μ- and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520, and U-48800. Drug Test Anal. 2022 Jul;14(7):1187-1199. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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U-48520

All Opioid Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

U-48520 Related Classifications

HY-130367 Related Classifications