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Art. -Nr.: HY-100415S1

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UKI-1-d₈ acetate

(Synonyms: WX-UK1-d₈ acetate; UKI-1C-d₈ acetate)

UKI-1-d₈ acetate (WX-UK1-d₈ acetate) is the deuterium labeled UKI-1 acetate. UKI-1 (WX-UK1) is a potent urokinase-type plasminogen activator (uPA) inhibitor with a K_i of 0.41 μM. UKI-1 is also a low molecular weight serine protease inhibitor. UKI-1 is a potent antimetastatic agent and inhibits the invasive capacity of carcinoma cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₄H₄₃D₈N₅O₇S
Molecular Weight:681.91

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

UKI-1-d₈ acetate Chemical Structure

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Biologische Aktivität
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Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 220355-63-5
Molecular Weight 681.91
Formel C₃₄H₄₃D₈N₅O₇S
SMILES

O=C(N1C([2H])([2H])C([2H])([2H])N(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(N)=N)=C3)=O)C([2H])([2H])C1([2H])[2H])OCC.CC(O)=O
Synonyms

WX-UK1-d₈ acetate; UKI-1C-d₈ acetate
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.