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  2. Progesterone Receptor
  3. Ulipristal

Ulipristal (Synonyms: CDB-3236; Deacetyl CDB-2914)

Cat. No.: HY-14959 Purity: >98.0%
Handling Instructions

Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system.

For research use only. We do not sell to patients.

Ulipristal Chemical Structure

Ulipristal Chemical Structure

CAS No. : 159811-51-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
50 mg USD 450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 750 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system[1].

In Vivo

Ulipristal (CDB 3236) may suppress the growth of uterine leiomyomatosis. By inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception[1].

Molecular Weight

433.58

Formula

C₂₈H₃₅NO₃

CAS No.

159811-51-5

SMILES

CN(C)C1=CC=C([[email protected]]2([H])C([[email protected]]3([H])[[email protected]@](CC[[email protected]]4(O)C(C)=O)([H])[[email protected]]4(C)C2)=C(CC5)C(CC3)=CC5=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (576.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3064 mL 11.5319 mL 23.0638 mL
5 mM 0.4613 mL 2.3064 mL 4.6128 mL
10 mM 0.2306 mL 1.1532 mL 2.3064 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (14.41 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 6.25 mg/mL (14.41 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

UlipristalCDB-3236Deacetyl CDB-2914CDB3236CDB 3236Deacetyl CDB2914Deacetyl CDB 2914Progesterone ReceptorNR3C3emergencycontraceptionuterineleiomyomaanti-progestationalanti-glucocorticoidanti-fertilityInhibitorinhibitorinhibit

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Product name:
Ulipristal
Cat. No.:
HY-14959
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