UNC7437
Based on 1 Customer Validation
UNC7437 is a inositol phosphate multikinase (IPMK) inhibitor, with an IC50 value of 26.2 nM. UNC7437 exhibits anti-proliferative activity against glioblastoma cells. UNC7437 decreases the accumulation of InsP4, InsP5, and InsP6 in cells. UNC7437 can be used for the study of TEN-negative glioblastoma models.
For research use only. We do not sell to patients.
- Purity: 99.58%
- CAS No.: 2967647-41-0
- Formula: C18H15NO3
- Molecular Weight:293.32
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
UNC7437 (400 nM, 48 h) shows significant anti-proliferative activity against human U251-MG glioblastoma cells[1].
UNC7437 (400 nM, 48 h) effectively inhibits inositol phosphate synthesis in human U251-MG glioblastoma cells, significantly decreasing the accumulation of InsP4, InsP5, and InsP6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2967647-41-0
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Appearance Solid
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Molecular Weight 293.32
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Formula C18H15NO3
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Color Light yellow to yellow
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SMILES
O=C(O)/C=C/C1=CC2=C(C3=CC(C)=CC(C)=C3)ON=C2C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)