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Cat. No.: HY-14444S

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Plinabulin-d₁

(Synonyms: NPI-2358-d₁)

Plinabulin-d1 is an active compound.

For research use only. We do not sell to patients.

CAS No.: 2054938-28-0
Formula: C₁₉H₁₉DN₄O₂
Molecular Weight:337.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Plinabulin-d₁ Chemical Structure

CAS No.: 2054938-28-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Plinabulin-d1 is an active compound.

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.5 nM Compound: MBRI-001	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30910474]
Jurkat	IC₅₀	4.3 nM Compound: 9	Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human Jurkat cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]
NCI-H1975	IC₅₀	9.3 nM Compound: MBRI-001	Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30910474]
NCI-H446	IC₅₀	22 nM Compound: 9	Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human NCI-H446 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]
NCI-H460	IC₅₀	33.2 nM Compound: 9	Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 28228362]

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2054938-28-0
Unlabeled Cas 714272-27-2
Molecular Weight 337.39
Formula C₁₉H₁₉DN₄O₂
SMILES

CC(C)(C)C(N=CN1)=C1/C([2H])=C2C(N/C(C(N/2)=O)=C\C3=CC=CC=C3)=O
Synonyms

NPI-2358-d₁
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- Application
Chemical Information
Purity & Documentation
References

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Plinabulin-d1

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Plinabulin-d1 Related Classifications

HY-14444S Related Classifications

Plinabulin-d₁

Plinabulin-d₁ Related Classifications