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Cat. No.: HY-N7562

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Ustusolate E

Ustusolate E is a drimane sesquiterpene with moderate cytotoxicity against HL-60 cells with an IC₅₀ value of 9.0 μM.

For research use only. We do not sell to patients.

CAS No.: 1175543-06-2
Formula: C₂₁H₂₆O₆
Molecular Weight:374.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Ustusolate E Chemical Structure

CAS No.: 1175543-06-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Ustusolate E is a drimane sesquiterpene with moderate cytotoxicity against HL-60 cells with an IC₅₀ value of 9.0 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>100 μM Compound: 8, Ustusolate E	Cytotoxicity against human A549 cells after 24 hrs by SRB assay Cytotoxicity against human A549 cells after 24 hrs by SRB assay	[PMID: 19769341]
HeLa	EC₅₀	5.9 μg/mL Compound: 7	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 19778087]
HL-60	IC₅₀	9 μM Compound: 8, Ustusolate E	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 19769341]
L5178Y	EC₅₀	0.6 μg/mL Compound: 7	Cytotoxicity against mouse L5178Y cells by MTT assay Cytotoxicity against mouse L5178Y cells by MTT assay	[PMID: 19778087]
PC-12	EC₅₀	7.2 μg/mL Compound: 7	Cytotoxicity against rat PC12 cells by MTT assay Cytotoxicity against rat PC12 cells by MTT assay	[PMID: 19778087]

Chemical Information

CAS No. 1175543-06-2
Molecular Weight 374.43
Formula C₂₁H₂₆O₆
SMILES

C[C@]([C@]12O)(CCC3)[C@@](C3(C)C)([H])[C@@H](C=C1COC2=O)OC(/C=C/C=C/C=O)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Microorganisms
Aspergillus ustus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhenyu Lu, et al. Sesquiterpenoids and benzofuranoids from the marine-derived fungus Aspergillus ustus 094102. J Nat Prod. 2009 Oct;72(10):1761-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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