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Cat. No.: HY-179431

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VDR ligand-1

VDR ligand-1 (compound 13a) is a nonsecosteroidal VDR agonist with an EC₅₀ value of 16 nM. VDR ligand-1 can be used for osteoporosis, psoriasis, and cancer research.

For research use only. We do not sell to patients.

Formula: C₁₉H₂₂B₁₀F₆O₄
Molecular Weight:536.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

VDR ligand-1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

VDR ligand-1 (compound 13a) is a nonsecosteroidal VDR agonist with an EC₅₀ value of 16 nM. VDR ligand-1 can be used for osteoporosis, psoriasis, and cancer research^[1].

Chemical Information

Molecular Weight 536.48
Formula C₁₉H₂₂B₁₀F₆O₄
SMILES

[H][C]1234[BH]567[BH]89%10[BH]%11%12%13[B]8%14%15(C%16=CC=C(OCC(O)=O)C=C%16)[BH]95%17[C]61%18(C%19=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C%19)[BH]%17%14%20[BH]%11%15%21[BH]%122([BH]%214%18%20)[BH]%10%1373
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mudiyanselage HNTN, et al. Design, synthesis and structural development of nonsecosteroidal VDR ligands based on the C,C'-diphenyl-m-carborane scaffold. Eur J Med Chem. 2026 Jan 15;302(Pt 2):118320. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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