VEGFR-2/STAT-3-IN-1
VEGFR-2/STAT-3-IN-1 (Compound 9f) is a dual inhibitor for VEGFR-2 (IC50=26.3 nM) and STAT-3 (IC50=5.63 nM). VEGFR-2/STAT-3-IN-1 inhibits the proliferation of cancer cells PANC1 and PC3 with IC50 of 0.14 and 0.10 µM. VEGFR-2/STAT-3-IN-1 induces apoptosis in PC3.
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- Fòrmula: C26H20N6O4
- Peso molecular:480.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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VEGFR2 26.3 nM (IC50) |
STAT3 5.63 nM (IC50) |
Chemical Information
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Peso molecular 480.47
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Fòrmula C26H20N6O4
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SMILES
O=C(N1C(C2=CC=CC=C2)=O)/C(C3=C1C=CC=C3)=N\NC(C4=C(C)N(C5=CC=C(OC)C=C5)N=N4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2/STAT-3-IN-1 Related Classifications
HY-161859 Related Classifications
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