Velaresol (Standard)
Velaresol (Standard) is the analytical standard of Velaresol. This product is intended for research and analytical applications. Velaresol (BW 12C) is a small molecule oxyhemoglobin stabilizer. Velaresol stabilizes hemoglobin’s oxy-conformation, shifts oxygen dissociation curves left, induces tumor hypoxia, alters radiosensitivity, protects normal tissues from radiation damage, and reduces sickled cell counts. Velaresol can be used for the research of cancer and sickle cell disease.
For research use only. We do not sell to patients.
- CAS No.: 77858-21-0
- Formula: C12H14O5
- Molecular Weight:238.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 77858-21-0
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Molecular Weight 238.24
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Formula C12H14O5
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SMILES
OC(CCCCOC1=C(C(O)=CC=C1)C=O)=O
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Synonyms
BW 12C (Standard); 12C79 (Standard); BW 12C79 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Honess DJ, et al. Effect of the manipulation of oxyhemoglobin status by BW12C on tumor thermosensitivity and on blood flow in tumor and normal tissues in mice. Int J Radiat Oncol Biol Phys. 1989 May;16(5):1187-90. [Content Brief]
[3]. van den Aardweg GJ, et al. Modification of the radiation response of pig skin by manipulation of tissue oxygen tension using anesthetics and administration of BW12C. Int J Radiat Oncol Biol Phys. 1989 May;16(5):1191-4. [Content Brief]
[5]. Kenny MW, et al. Preservation of deformability (filterability) of sickle cells by BW12C during progressive deoxygenation. Br J Haematol. 1983 Nov;55(3):465-71. [Content Brief]
[6]. Falk SJ, et al. BW12C perturbs normal and tumour tissue oxygenation and blood flow in man. Radiother Oncol. 1994 Sep;32(3):210-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)