VinclozolinM2-2204
Based on 1 Customer Validation
VinclozolinM2-2204 is a androgen receptor (AR) AUTOTAC degrader, with an DC50 of 200 nM in LNCaP prostate cancer cells. VinclozolinM2-2204 induces the formation of AR+LC3+ autophagic membranes. VinclozolinM2-2204 can be used for the research of cancer.(Pink: AR inhibitor (HY-168296); Black: linker (HY-128833); Blue: CRBN Ligand (HY-168293))
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.00%
- Formel: C43H51Cl2N3O9
- Molecular Weight:824.79
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Speicherung:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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Appearance Solid
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Molecular Weight 824.79
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Formel C43H51Cl2N3O9
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Color White to off-white
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SMILES
O[C@H](CNCCOCCOCCNC(N(C1=CC(Cl)=CC(Cl)=C1)C(C(C)(O)C=C)=O)=O)COC2=CC(OCCC3=CC=CC=C3)=C(OCCC4=CC=CC=C4)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
DMSO : ≥ 100 mg/mL (121.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2124 mL | 6.0621 mL | 12.1243 mL | 30.3107 mL |
| 5 mM | 0.2425 mL | 1.2124 mL | 2.4249 mL | 6.0621 mL | |
| 10 mM | 0.1212 mL | 0.6062 mL | 1.2124 mL | 3.0311 mL | |
| 15 mM | 0.0808 mL | 0.4041 mL | 0.8083 mL | 2.0207 mL | |
| 20 mM | 0.0606 mL | 0.3031 mL | 0.6062 mL | 1.5155 mL | |
| 25 mM | 0.0485 mL | 0.2425 mL | 0.4850 mL | 1.2124 mL | |
| 30 mM | 0.0404 mL | 0.2021 mL | 0.4041 mL | 1.0104 mL | |
| 40 mM | 0.0303 mL | 0.1516 mL | 0.3031 mL | 0.7578 mL | |
| 50 mM | 0.0242 mL | 0.1212 mL | 0.2425 mL | 0.6062 mL | |
| 60 mM | 0.0202 mL | 0.1010 mL | 0.2021 mL | 0.5052 mL | |
| 80 mM | 0.0152 mL | 0.0758 mL | 0.1516 mL | 0.3789 mL | |
| 100 mM | 0.0121 mL | 0.0606 mL | 0.1212 mL | 0.3031 mL |
VinclozolinM2-2204 Related Classifications
HY-161741 Related Classifications
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