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Cat. No.: HY-110148R

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WWL113 (Standard)

WWL113 (Standard) is the analytical standard of WWL113 (HY-110148). This product is intended for research and analytical applications. WWL113 is a selective and orally active Ces3 and Ces1f inhibitor, with IC₅₀ values of 120 nM and 100 nM for Ces3 and Ces1f, respectively. WWL113 appears to show excellent selectivity for the 60-K_da serine hydrolase (or hydrolases).

For research use only. We do not sell to patients.

CAS No.: 947669-86-5
Formula: C₂₉H₂₆N₂O₄
Molecular Weight:466.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

WWL113 (Standard) Chemical Structure

CAS No.: 947669-86-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 947669-86-5
Molecular Weight 466.53
Formula C₂₉H₂₆N₂O₄
SMILES

CN(CC1=CC(C2=CC=NC=C2)=CC=C1)C(OC3=CC=C(C4=CC=C(C(OCC)=O)C=C4)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Dominguez, E., Galmozzi, A., Chang, J.W., et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat. Chem. Biol. 10(2), 113-121 (2014). [Content Brief]

[2]. Galmozzi, et al. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Rep. 2014 Dec 11;9(5):1584-1593. [Content Brief]

[3]. Turcotte C, et al. The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors. J Immunol. 2017 Apr 15;198(8):3255-3263. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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