YT-8-8
Based on 1 Customer Validation
YT-8-8 is a ligand of p62-ZZ domain. YT-8-8 can activate p62-dependent selective macroautophagy. YT-8-8 can be used for AUTOTAC design.
For research use only. We do not sell to patients.
- Purity: 98.57%
- CAS No.: 892572-23-5
- Formula: C18H23FN2O2
- Molecular Weight:318.39
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
Chemical Information
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CAS No. 892572-23-5
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Appearance Solid
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Molecular Weight 318.39
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Formula C18H23FN2O2
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Color White to off-white
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SMILES
OCCNCCNCC1=CC(OCC2=CC=C(F)C=C2)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 116.67 mg/mL (366.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1408 mL | 15.7040 mL | 31.4080 mL | 78.5201 mL |
| 5 mM | 0.6282 mL | 3.1408 mL | 6.2816 mL | 15.7040 mL | |
| 10 mM | 0.3141 mL | 1.5704 mL | 3.1408 mL | 7.8520 mL | |
| 15 mM | 0.2094 mL | 1.0469 mL | 2.0939 mL | 5.2347 mL | |
| 20 mM | 0.1570 mL | 0.7852 mL | 1.5704 mL | 3.9260 mL | |
| 25 mM | 0.1256 mL | 0.6282 mL | 1.2563 mL | 3.1408 mL | |
| 30 mM | 0.1047 mL | 0.5235 mL | 1.0469 mL | 2.6173 mL | |
| 40 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9630 mL | |
| 50 mM | 0.0628 mL | 0.3141 mL | 0.6282 mL | 1.5704 mL | |
| 60 mM | 0.0523 mL | 0.2617 mL | 0.5235 mL | 1.3087 mL | |
| 80 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 100 mM | 0.0314 mL | 0.1570 mL | 0.3141 mL | 0.7852 mL |