Zocilurtatug
Based on 1 Customer Validation
Zocilurtatug (ZL-1310 Antibody) is a human monoclonal antibody targeting DLL3. Zocilurtatug serves as the targeting antibody component of antibody-drug conjugates (ADCs) and is used in research related to small cell lung cancer and neuroendocrine carcinoma. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
For research use only. We do not sell to patients.
- Purity: 99.50%
- CAS No.: 3058592-86-9
- Molecular Weight:145.546 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Human IgG1 kappa
Human
Antibody-drug conjugates (ADCs) are a novel class of anti-tumor drugs, consisting of three parts: a targeting antibody—which specifically recognizes tumor cell surface antigens and acts as a "navigator"; a linker; and a cytotoxic payload. Zocilurtatug can serve as the targeting antibody component of an ADC, conjugated with a topoisomerase I inhibitor (camptothecin derivative) payload via a cleavable linker to form the complete ADC Zocilurtatug pelitecan. This allows for precise delivery of the cytotoxic payload to DLL3-positive tumor cells, killing tumor cells while minimizing damage to normal cells[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
DLL3
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
IgG1-kappa
ELISA, FACS, Functional assay
-
Loaded Zocilurtatug on AHC2 biosensor, can bind Delta-like protein 3/DLL3 Protein, Human (HEK293, HY-P700456) with an affinity constant of 9.642E-09 M as determined in BLI assay.
Chemical Information
-
CAS No. 3058592-86-9
-
Appearance Liquid
-
Molecular Weight 145.546 kDa
-
Color Colorless to light yellow
-
SMILES
[Zocilurtatug]
-
Synonyms
ZL-1310 Antibody
-
Shipping
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (256 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zocilurtatug Related Classifications
HY-P992148 Related Classifications
Powered by Bioz