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Cat. No.: HY-105064C

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Zoniporide dihydrochloride

(Synonyms: CP-597396 dihydrochloride)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 (NHE-1). Zoniporide dihydrochloride inhibits NHE1 dependent 22Na⁺ uptake in vitro with an IC₅₀ of 14 nM. Zoniporide has antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 241799-10-0
Formula: C₁₇H₁₈Cl₂N₆O
Molecular Weight:393.27

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Zoniporide dihydrochloride Chemical Structure

CAS No.: 241799-10-0

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Description

Chemical Information

CAS No. 241799-10-0
Molecular Weight 393.27
Formula C₁₇H₁₈Cl₂N₆O
SMILES

N=C(N)NC(C1=C(C2CC2)N(C3=C4C(N=CC=C4)=CC=C3)N=C1)=O.[H]Cl.[H]Cl
Synonyms

CP-597396 dihydrochloride
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Carbohydr Polym

Slc9a1 plays a vital role in chitosan oligosaccharide transport across the intestinal mucosa of mice. [Abstract]

2023 Jan 1:299:120179. PMID: 36876794
J Biol Chem

Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid. [Abstract]

2021 Oct;297(4):101166. PMID: 34487763

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marala RB, et al. Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1. Eur J Pharmacol. 2002 Sep 6;451(1):37-41. [Content Brief]

[2]. Sanhueza C, et al. Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):81-91. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Zoniporide dihydrochloride

2 Cited Publications

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Zoniporide dihydrochloride

Publications Citing Use of MedChemExpress (MCE) Zoniporide dihydrochloride

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Publications (2)

Purity & Documentation

References

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Zoniporide dihydrochloride Related Classifications

HY-105064C Related Classifications