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β-Bisabolene 

Cat. No.: HY-136552
Handling Instructions

β-Bisabolene is a sesquiterpene isolated from opoponax (Commiphora guidotti). β-Bisabolene, an anti-cancer agent, can be used for the study of breast cancer.

For research use only. We do not sell to patients.

β-Bisabolene Chemical Structure

β-Bisabolene Chemical Structure

CAS No. : 495-61-4

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Description

β-Bisabolene is a sesquiterpene isolated from opoponax (Commiphora guidotti). β-Bisabolene, an anti-cancer agent, can be used for the study of breast cancer[1].

In Vitro

β‐bisabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC50 values of >200 µg/ml, 65.49 µg/ml, and 48.99 µg/ml, respectively. It against normal MCF‐10A, MCF‐7, MDA‐MB‐231, SKBR3 and BT474 cells with IC50 values of 114.3 µg/ml, 66.91 µg/ml, 98.39 µg/ml, 70.62 µg/ml and 74.3 µg/ml, respectively[1].

In Vivo

β‐bisabolene is effective in reducing the growth of transplanted 4T1 mammary tumours in vivo (37.5% reduction in volume by endpoint)[1].

Molecular Weight

204.35

Formula

C₁₅H₂₄

CAS No.

495-61-4

SMILES

C/C(C)=C\CCC([[email protected]@H]1CC=C(C)CC1)=C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

β-BisaboleneOthersEph4MG13614T1MCF‐10AMCF‐7MDA‐MB‐231SKBR3Inhibitorinhibitorinhibit

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