β-Bisabolene 

β-Bisabolene is a sesquiterpene isolated from opoponax (Commiphora guidotti). β-Bisabolene, an anti-cancer agent, can be used for the study of breast cancer^[1].

β‐bisabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC₅₀ values of >200 µg/ml, 65.49 µg/ml, and 48.99 µg/ml, respectively. It against normal MCF‐10A, MCF‐7, MDA‐MB‐231, SKBR3 and BT474 cells with IC₅₀ values of 114.3 µg/ml, 66.91 µg/ml, 98.39 µg/ml, 70.62 µg/ml and 74.3 µg/ml, respectively^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

β‐bisabolene is effective in reducing the growth of transplanted 4T1 mammary tumours in vivo (37.5% reduction in volume by endpoint)^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

204.35

C₁₅H₂₄

495-61-4

C/C(C)=C\CCC([[email protected]@H]1CC=C(C)CC1)=C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Syn Kok Yeo,et al. β-Bisabolene, a Sesquiterpene From the Essential Oil Extract of Opoponax (Commiphora Guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines. Phytother Res. 2016 Mar;30(3):418-25.  [Content Brief]