1-Hexadecanol-d₅

Name: 1-Hexadecanol-d 5
Brand: MedChemExpress
SKU: HY-B1465S2
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1465S2 Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1-Hexadecanol-d₅ is the deuterium labeled 1-Hexadecanol[1]. 1-Hexadecanol is a fatty alcohol, a lipophilic substrate[2].

For research use only. We do not sell to patients.

1-Hexadecanol-d<sub>5</sub> Chemical Structure

1-Hexadecanol-d₅ Chemical Structure

CAS No. : 1219799-18-4

Size	Price	Stock	Quantity
5 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 1-Hexadecanol-d₅:

1-Hexadecanol In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

1-Hexadecanol-d₅ is the deuterium labeled 1-Hexadecanol[1]. 1-Hexadecanol is a fatty alcohol, a lipophilic substrate[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

247.47

Formula

C₁₆H₂₉D₅O

CAS No.

1219799-18-4

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])CCCCCCCCCCCCCC([2H])([2H])CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (202.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.0409 mL	20.2045 mL	40.4089 mL
5 mM	0.8082 mL	4.0409 mL	8.0818 mL
10 mM	0.4041 mL	2.0204 mL	4.0409 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 1.25 mg/mL (5.05 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (240 KB) HNMR (686 KB) RP-HPLC (1002 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Nawale L, et al. Anti-proliferative effect of novel primary cetyl alcohol derived sophorolipids against human cervical cancer cells HeLa. PLoS One. 2017 Apr 18;12(4):e0174241. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.0409 mL	20.2045 mL	40.4089 mL	101.0223 mL
	5 mM	0.8082 mL	4.0409 mL	8.0818 mL	20.2045 mL
	10 mM	0.4041 mL	2.0204 mL	4.0409 mL	10.1022 mL
	15 mM	0.2694 mL	1.3470 mL	2.6939 mL	6.7348 mL
	20 mM	0.2020 mL	1.0102 mL	2.0204 mL	5.0511 mL
	25 mM	0.1616 mL	0.8082 mL	1.6164 mL	4.0409 mL
	30 mM	0.1347 mL	0.6735 mL	1.3470 mL	3.3674 mL
	40 mM	0.1010 mL	0.5051 mL	1.0102 mL	2.5256 mL
	50 mM	0.0808 mL	0.4041 mL	0.8082 mL	2.0204 mL
	60 mM	0.0673 mL	0.3367 mL	0.6735 mL	1.6837 mL
	80 mM	0.0505 mL	0.2526 mL	0.5051 mL	1.2628 mL
	100 mM	0.0404 mL	0.2020 mL	0.4041 mL	1.0102 mL