10-Hydroxycanthin-6-one

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10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent.

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10-Hydroxycanthin-6-one Chemical Structure

CAS No. : 86293-41-6

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Description	10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent^[1].
In Vitro	10-Hydroxycanthin-6-one shows antibacterial activity with a MIC of 15.62 µg/mL for B. cereus^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 10-Hydroxycanthin-6-one Related Antibodies
Molecular Weight	236.23
Formula	C₁₄H₈N₂O₂
CAS No.	86293-41-6
SMILES	O=C1N2C3=C(N=CC=C3C4=C2C=CC(O)=C4)C=C1
Structure Classification	Alkaloids Pyridine Alkaloids Alkaloids Indole Alkaloids Phenols Monophenols
Initial Source	Plants Simaroubaceae Brucea javanica (L.) Merr.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (274 KB) Handling Instructions (2659 KB)
References	[1]. N Fukamiya, et al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3. [Content Brief]

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

10-Hydroxycanthin-6-one86293-41-6OthersAntileukemicalkaloidBrucea antidysentericaAntitumor agentInhibitorinhibitorinhibit

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10-Hydroxycanthin-6-one