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Cat. No.: HY-129240

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13-cis Acitretin

(Synonyms: Isoacitretin; Ro 13-7652)

13-cis Acitretin (Isoacitretin; Ro 13-7652) is a retinoid and the major in vivo metabolite of etretinate. 13-cis Acitretin is formed via in vivo isomerization of etretinate. 13-cis Acitretin serves as the primary metabolite in blood.

For research use only. We do not sell to patients.

CAS No.: 69427-46-9
Formula: C₂₁H₂₆O₃
Molecular Weight:326.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

13-cis Acitretin Chemical Structure

CAS No.: 69427-46-9

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

13-cis Acitretin is formed via in vivo isomerization of Etretinate. 13-cis Acitretin serves as the major metabolite in blood^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 69427-46-9
Molecular Weight 326.43
Formula C₂₁H₂₆O₃
SMILES

O=C(/C=C(\C=C\C=C(\C=C\C1=C(C=C(C(C)=C1C)OC)C)C)C)O
Synonyms

Isoacitretin; Ro 13-7652
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Stuck AE, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989;27(3):301-304. [Content Brief]

[2]. Kumar A, et al. Stability-indicating validation of acitretin and isoacitretin in human plasma by LC-ESI-MS/MS bioanalytical method and its application to pharmacokinetic analysis. Biomed Chromatogr. 2011;25(6):680-688. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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