(1R)-BMS-986408
Based on 1 Customer Validation
(1R)-BMS-986408 is an orally active dual DGK α/ζ inhibitor that restores T cell-mediated anti-tumor immunity by enhancing T cell signaling.
For research use only. We do not sell to patients.
- Purity: 99.03%
- CAS No.: 2618418-11-2
- Formula: C27H31F3N6O
- Molecular Weight:512.57
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 2618418-11-2
-
Appearance Solid
-
Molecular Weight 512.57
-
Formula C27H31F3N6O
-
Color White to off-white
-
SMILES
CC[C@H]1CN([C@@H](CN1C2=NC(N(C3=CC=C(N=C32)C#N)C)=O)CC)[C@@H](C4=CC=C(C=C4)C(F)(F)F)CC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)