2-Hydroxypalmitic acid-13C2
2-Hydroxypalmitic acid-13C2 is the 13C-labeled 2-Hydroxypalmitic acid (HY-N7814). 2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection.
For research use only. We do not sell to patients.
- Formula: C1413C2H32O3
- Molecular Weight:274.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 764-67-0
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Molecular Weight 274.41
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Formula C1413C2H32O3
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SMILES
CCCCCCCCCCCCCC[13CH](O)[13C](O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Hydroxypalmitic acid-13C2 Related Classifications
HY-N7814S1 Related Classifications
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Keywords
- 2-Hydroxypalmitic acid-13C2
- Isotope-Labeled Compounds
- Endogenous Metabolite
- Drug Intermediate
- acyl-CoA synthetases Faa1
- Saccharomyces cerevisiae AOY13 cells
- glycerophospholipids
- Saccharomyces cerevisiae BY4741 cells
- MPO1 gene
- odd-numbered phosphatidylcholine
- phytosphingosine metabolic pathway
- yeast cells
- acyl-CoA synthetases Faa4
- Saccharomyces cerevisiae 4378 cells
- Inhibitor
- inhibitor
- inhibit