2-Phenyl-2-(1-piperidinyl)propane
Based on 1 Customer Validation
2-Phenyl-2-(1-piperidinyl)propane is a selective and reversible human CYP2B6 inhibitor with an IC50 of 5.1 μM and a Ki of 5.6. 2-Phenyl-2-(1-piperidinyl)propane inhibits CYP2D6 (IC50=74 μM), CYP3A (IC50=200 μM).
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 92321-29-4
- Formula: C14H21N
- Molecular Weight:203.32
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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CYP2B6 5.1 μM (IC50) |
CYP2B6 5.6 μM (Ki) |
CYP2D6 74 μM (IC50) |
CYP3A 200 μM (IC50) |
CYP1A2 >300 μM (IC50) |
CYP2A6 >300 μM (IC50) |
CYP2C8 >300 μM (IC50) |
CYP2C9 >300 μM (EC50) |
CYP2C19 >300 μM (IC50) |
CYP2E1 >300 μM (IC50) |
Chemical Information
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CAS No. 92321-29-4
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Appearance Liquid (Density: 0.969±0.06 g/cm3)
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Molecular Weight 203.32
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Formula C14H21N
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Color Colorless to light yellow
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SMILES
CC(N1CCCCC1)(C2=CC=CC=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (245.92 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9184 mL | 24.5918 mL | 49.1836 mL | 122.9589 mL |
| 5 mM | 0.9837 mL | 4.9184 mL | 9.8367 mL | 24.5918 mL | |
| 10 mM | 0.4918 mL | 2.4592 mL | 4.9184 mL | 12.2959 mL | |
| 15 mM | 0.3279 mL | 1.6395 mL | 3.2789 mL | 8.1973 mL | |
| 20 mM | 0.2459 mL | 1.2296 mL | 2.4592 mL | 6.1479 mL | |
| 25 mM | 0.1967 mL | 0.9837 mL | 1.9673 mL | 4.9184 mL | |
| 30 mM | 0.1639 mL | 0.8197 mL | 1.6395 mL | 4.0986 mL | |
| 40 mM | 0.1230 mL | 0.6148 mL | 1.2296 mL | 3.0740 mL | |
| 50 mM | 0.0984 mL | 0.4918 mL | 0.9837 mL | 2.4592 mL | |
| 60 mM | 0.0820 mL | 0.4099 mL | 0.8197 mL | 2.0493 mL | |
| 80 mM | 0.0615 mL | 0.3074 mL | 0.6148 mL | 1.5370 mL | |
| 100 mM | 0.0492 mL | 0.2459 mL | 0.4918 mL | 1.2296 mL |
2-Phenyl-2-(1-piperidinyl)propane Related Classifications
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