2-Phenylpropionic acid-d3
2-Phenylpropionic acid-d3 is the deuterated-labeled 2-Phenylpropionic acid (HY-W015608). 2-Phenylpropionic acid is an intermediate in the metabolism of alpha-Methylstyrene. 2-Phenylpropionic acid covalently binds to rat liver protein. 2-Phenylpropionic acid can be used in the research of nonsteroidal anti-inflammatory agents.
For research use only. We do not sell to patients.
- CAS No.: 192198-54-2
- Formula: C9H7D3O2
- Molecular Weight:153.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 192198-54-2
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Unlabeled Cas 492-37-5
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Molecular Weight 153.19
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Formula C9H7D3O2
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SMILES
O=C(O)C(C1=CC=CC=C1)C([2H])([2H])[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Li C, et al. Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. Chem Res Toxicol. 2002 Nov;15(11):1480-7. [Content Brief]
[2]. Li C, et al. In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. J Pharmacol Exp Ther. 2003 Apr;305(1):250-6. [Content Brief]
[3]. De Costa KS, et al. Metabolism and disposition of alpha-methylstyrene in rats. Drug Metab Dispos. 2001 Feb;29(2):166-71. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Phenylpropionic acid-d3 Related Classifications
HY-W015608S Related Classifications
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