2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3-Butynoic acid

3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase. 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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3-Butynoic acid Chemical Structure

3-Butynoic acid Chemical Structure

CAS No. : 2345-51-9

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Based on 1 publication(s) in Google Scholar

3-Butynoic acid Related Antibodies

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Description

3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase[1]. 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

84.07

Formula

C4H4O2
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

C#CCC(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (1189.48 mM; Need ultrasonic)

DMSO : ≥ 100 mg/mL (1189.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 11.8948 mL 59.4743 mL 118.9485 mL
5 mM 2.3790 mL 11.8948 mL 23.7897 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.99%

COA (246 KB) HNMR (112 KB) GC (279 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 11.8948 mL 59.4742 mL 118.9485 mL 297.3712 mL
5 mM 2.3790 mL 11.8948 mL 23.7897 mL 59.4742 mL
10 mM 1.1895 mL 5.9474 mL 11.8948 mL 29.7371 mL
15 mM 0.7930 mL 3.9649 mL 7.9299 mL 19.8247 mL
20 mM 0.5947 mL 2.9737 mL 5.9474 mL 14.8686 mL
25 mM 0.4758 mL 2.3790 mL 4.7579 mL 11.8948 mL
30 mM 0.3965 mL 1.9825 mL 3.9649 mL 9.9124 mL
40 mM 0.2974 mL 1.4869 mL 2.9737 mL 7.4343 mL
50 mM 0.2379 mL 1.1895 mL 2.3790 mL 5.9474 mL
60 mM 0.1982 mL 0.9912 mL 1.9825 mL 4.9562 mL
80 mM 0.1487 mL 0.7434 mL 1.4869 mL 3.7171 mL
100 mM 0.1189 mL 0.5947 mL 1.1895 mL 2.9737 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-Butynoic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Butynoic acid2345-51-9Endogenous MetaboliteAcyl CoA dehydrogenaseInhibitorinhibitorinhibit

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