3'-O-Acetylthymidine
3'-O-Acetylthymidine, a purine nucleoside analog, is an inhibitor of ribonuclease A.
For research use only. We do not sell to patients.
- CAS No.: 21090-30-2
- Formula: C12H16N2O6
- Molecular Weight:284.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
RNase A 42 μM (Ki) |
RNase A 197 μM (IC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| C8166 | ED50 |
>200 μM
Compound: 1c
|
Compound was tested for its ability to inhibit the replication of HIV-1 in C8166 T-cells
Compound was tested for its ability to inhibit the replication of HIV-1 in C8166 T-cells
|
10.1016/S0960-894X(00)80316-9 |
Chemical Information
-
CAS No. 21090-30-2
-
Molecular Weight 284.27
-
Formula C12H16N2O6
-
SMILES
CC1=CN([C@H]2C[C@H](OC(C)=O)[C@@H](CO)O2)C(NC1=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ghosh KS, Debnath J, Dutta P, Sahoo BK, Dasgupta S. Exploring the potential of 3'-O-carboxy esters of thymidine as inhibitors of ribonuclease A and angiogenin. Bioorg Med Chem. 2008;16(6):2819-2828. [Content Brief]
[2]. Ghosh KS, Debnath J, Pathak T, Dasgupta S. Using proton nuclear magnetic resonance to study the mode of ribonuclease A inhibition by competitive and noncompetitive inhibitors. Bioorg Med Chem Lett. 2008;18(20):5503-5506. [Content Brief]
[3]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3'-O-Acetylthymidine Related Classifications
HY-N8525 Related Classifications
Powered by Bioz