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Cat. No.: HY-N9981

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5β-Hydroxybufotalin

Name: 5β-Hydroxybufotalin
Brand: MedChemExpress
SKU: HY-N9981
Price: 362.00 USD
Availability: InStock
Rating: 5 (1 reviews)

5β-Hydroxybufotalin (compound 6) is an anticancer agent that can effectively inhibit the growth activity of cancer cells. 5β-Hydroxybufotalin is also a natural product obtained from the chinese traditional drug Ch'an Su.

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CAS No.: 74531-99-0
Formule: C₂₆H₃₆O₇
Masse moléculaire:460.56

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

5β-Hydroxybufotalin Chemical Structure

CAS No.: 74531-99-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	IC₅₀	0.11 μg/mL Compound: 6	Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay Cytotoxicity against human BxPC3 cells after 72 hrs by MTT assay	[PMID: 11575946]
DU-145	IC₅₀	0.024 μg/mL Compound: 6	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 11575946]
HL-60	IC₅₀	<0.01 μg/mL Compound: 6	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 11575946]
KB	IC₅₀	0.2 μg/mL Compound: 6	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 11575946]
KM-20L2	IC₅₀	0.034 μg/mL Compound: 6	Cytotoxicity against human KM20L2 cells after 72 hrs by MTT assay Cytotoxicity against human KM20L2 cells after 72 hrs by MTT assay	[PMID: 11575946]
MCF7	IC₅₀	0.046 μg/mL Compound: 6	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 11575946]
MH60	IC₅₀	>25 μg/mL Compound: 6	Cytotoxicity against mouse MH60 cells after 72 hrs by MTT assay Cytotoxicity against mouse MH60 cells after 72 hrs by MTT assay	[PMID: 11575946]
NCI-H460	IC₅₀	0.048 μg/mL Compound: 6	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 11575946]
SF-268	IC₅₀	0.033 μg/mL Compound: 6	Cytotoxicity against human SF268 cells after 72 hrs by MTT assay Cytotoxicity against human SF268 cells after 72 hrs by MTT assay	[PMID: 11575946]

Chemical Information

CAS No. 74531-99-0
Masse moléculaire 460.56
Formule C₂₆H₃₆O₇
SMILES

C[C@@]12[C@](C(C=C3)=COC3=O)([H])[C@H](C[C@@]1([C@@]4([H])[C@]([C@@]5([C@](CC4)(C[C@H](CC5)O)O)C)([H])CC2)O)OC(C)=O
Structure Classification
- Steroids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nogawa T, et al. Isolation and structure of five new cancer cell growth inhibitory bufadienolides from the Chinese traditional drug Ch'an Su. J Nat Prod. 2001 Sep;64(9):1148-52. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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