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Amcasertib (Synonyms: BBI503)

Cat. No.: HY-17602 Purity: 98.70%
Handling Instructions

Amcasertib is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases.

For research use only. We do not sell to patients.

Amcasertib Chemical Structure

Amcasertib Chemical Structure

CAS No. : 1129403-56-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 202 In-stock
Estimated Time of Arrival: December 31
1 mg USD 65 In-stock
Estimated Time of Arrival: December 31
5 mg USD 170 In-stock
Estimated Time of Arrival: December 31
10 mg USD 260 In-stock
Estimated Time of Arrival: December 31
25 mg USD 530 In-stock
Estimated Time of Arrival: December 31
50 mg USD 860 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Amcasertib is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases.

Clinical Trial
Molecular Weight

539.69

Formula

C₃₁H₃₃N₅O₂S

CAS No.

1129403-56-0

SMILES

O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (55.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8529 mL 9.2646 mL 18.5292 mL
5 mM 0.3706 mL 1.8529 mL 3.7058 mL
10 mM 0.1853 mL 0.9265 mL 1.8529 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.25 mg/mL (2.32 mM); Clear solution

*All of the co-solvents are provided by MCE.
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

AmcasertibBBI503BBI 503BBI-503OthersInhibitorinhibitorinhibit

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Product Name:
Amcasertib
Cat. No.:
HY-17602
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