1. Saccharides and Glycosides
  2. Hosenkoside K

Hosenkoside K 

Cat. No.: HY-N2243 Purity: 99.29%
Handling Instructions

Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.

For research use only. We do not sell to patients.

Hosenkoside K Chemical Structure

Hosenkoside K Chemical Structure

CAS No. : 160896-49-1

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Description

Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.

In Vivo

The mean peak concentrations of hosenkoside K in rats after oral administration of total saponins of Semen Impatientis is 511.11±234.07 ng/mL, occurring at times of 0.46 h. The terminal half-lives of hosenkoside A is 4.96±1.75 h[1].

Molecular Weight

1141.29

Formula

C₅₄H₉₂O₂₅

CAS No.

160896-49-1

SMILES

C[[email protected]@]([[email protected]@]1(CC[[email protected]@]23CC[[email protected]]([[email protected]@H](C)CO[[email protected]@H]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]4O)O)O[[email protected]@H]4CO)([H])OC3)C)(CC[[email protected]@]5([H])[[email protected]]6(C)CO[[email protected]@H]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]7O)O)O[[email protected]@H]7CO)[[email protected]@](CC[[email protected]]1([H])[[email protected]]2O)([H])[[email protected]]5(CC[[email protected]@H]6O[[email protected]@](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]8O)([H])[[email protected]@H]8O[[email protected]]([[email protected]@H]([[email protected]@H](O)[[email protected]@H]9O)O)([H])O[[email protected]@H]9CO)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Animal Administration

Male Wistar rats (7 weeks old, 220±20 g, n=6) are fasted for 12 h. Total saponins of Semen Impatientis at a dose of 300 mg (in 10 mL)/kg are orally administered to rats using a gastric gavage tube. The doses of hosenkoside A is12.4 mg/kg for an oral dose of 300 mg/kg total saponins. Blood samples (0.20 mL) are collected from suborbital vein into heparinized tubes before administration (0 min), and 0.08, 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 12 and 24 h after dosing.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Hosenkoside K
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