1. Metabolic Enzyme/Protease
  2. Indoleamine 2,3-Dioxygenase (IDO)
  3. IDO-IN-5

IDO-IN-5  (Synonyms: NLG-1489)

Cat. No.: HY-18770 Purity: 95.16% ee.: 95.39%
COA Handling Instructions

IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.

For research use only. We do not sell to patients.

IDO-IN-5 Chemical Structure

IDO-IN-5 Chemical Structure

CAS No. : 1402837-79-9

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10 mg USD 1440 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.

IC50 & Target[1]

IDO

1-10 μM (IC50)

In Vitro

IDO-IN-5 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-5 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

316.37

Formula

C18H21FN2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H](CC1)CC[C@]1([H])[C@H](O)C[C@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.90% ee.: 97.93%

References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
IDO-IN-5
Cat. No.:
HY-18770
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