PF-02575799

Cat. No.: HY-100333: FAQs
Data Sheet Handling Instructions

Molarity Calculator

PF-02575799 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC₅₀ of 0.77±0.29 nM.

For research use only. We do not sell to patients.

PF-02575799 Chemical Structure

CAS No. : 863491-70-7

Size		Stock
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Protocol
Purity & Documentation
Customer Review

Description	PF-02575799 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC₅₀ of 0.77±0.29 nM.
IC₅₀ & Target	IC50: 0.77±0.29 nM (MTP)^[1]
In Vitro	PF-02575799 is compound 13 from the reference^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. PF-02575799 Related Antibodies
In Vivo	PF-02575799 produces appreciable triglyceride effects at its minimally effective dose (10 mg/kg). PF-02575799 significant increase alanine transaminase at 100 mg/kg^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	680.77
Formula	C₄₂H₃₇FN₄O₄
CAS No.	863491-70-7
SMILES	O=C(C1=CC=C2N=C(NC(C3=CC=CC=C3C4=CC=C(OC(C)C)C=C4)=O)C=CC2=C1)N[C@@H](C5=CC=CC=C5)C(N(CC6=CC=C(F)C=C6)C)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)

Animal Administration
^[1]

Rats^[1]

Spray-dried dispersions formulated PF-02575799 is tested in a seven-day rat model. Food intake, body weight, liver TG, as well as serum alanine transaminase (ALT) are measured. In the definitive study, dose effect relationships are examined (PF-02575799 1, 3, 10, 30 and 100 mg/kg q.d.) and systemic exposures are measured^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-02575799863491-70-7PF02575799PF 02575799Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name			Lot #
Applicant Name *			Email Address *
Phone Number			Department *
Organization Name *			Country or Region *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

PF-02575799

PF-02575799 Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Protocol

Purity & Documentation

Customer Review