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Miridesap (Synonyms: CPHPC; Ro63-8695; GSK2315698)

Cat. No.: HY-101861 Purity: 98.05%
Handling Instructions

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.

For research use only. We do not sell to patients.
Miridesap Chemical Structure

Miridesap Chemical Structure

CAS No. : 224624-80-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
5 mg USD 50 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.

IC50 & Target

SAP[1]

In Vitro

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles[1]. Miridesap depletes circulating SAP almost completely but leaves some SAP in amyloid deposits for specific recognition by subsequently administered therapeutic anti-SAP antibodies[2].

Clinical Trial
References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.9380 mL 14.6899 mL 29.3798 mL
5 mM 0.5876 mL 2.9380 mL 5.8760 mL
10 mM 0.2938 mL 1.4690 mL 2.9380 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

340.37

Formula

C₁₆H₂₄N₂O₆

CAS No.

224624-80-0

SMILES

O=C(N1[[email protected]](CCC1)C(O)=O)CCCCC(N2[[email protected]](CCC2)C(O)=O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 300 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Miridesap
Cat. No.:
HY-101861
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