1. Metabolic Enzyme/Protease
  2. Isocitrate Dehydrogenase (IDH)

Mutant IDH1-IN-4 

Cat. No.: HY-114459 Purity: >99.0%
Handling Instructions

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

For research use only. We do not sell to patients.

Mutant IDH1-IN-4 Chemical Structure

Mutant IDH1-IN-4 Chemical Structure

CAS No. : 1416270-18-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 935 In-stock
Estimated Time of Arrival: December 31
5 mg USD 850 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1].

IC50 & Target

IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1].

References
Molecular Weight

438.56

Formula

C₂₅H₃₄N₄O₃

CAS No.

1416270-18-2

SMILES

N#CC1=C(N2C[[email protected]@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Mutant IDH1-IN-4
Cat. No.:
HY-114459
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Mutant IDH1-IN-4

Cat. No.: HY-114459