Mutant IDH1-IN-4
Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.
For research use only. We do not sell to patients.
- CAS No.: 1416270-18-2
- Formula: C25H34N4O3
- Molecular Weight:438.56
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1].
Chemical Information
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CAS No. 1416270-18-2
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Appearance Solid
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Molecular Weight 438.56
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Formula C25H34N4O3
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Color Light yellow to yellow
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SMILES
N#CC1=C(N2C[C@@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (264 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. US20170210749A1.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)