Guttiferae Extract

Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca²⁺ levels by activating Ca²⁺-conducting non-selective canonical TRPC6 channels and triggers adipose tissue thermogenesis via the Dlat-AMPK signaling axis to suppress obesity. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model.

8,8a-Dihydro-8-hydroxygambogic acid is a natural product, that can be isolated from the resin of Garcinia hanburyi. 8,8a-Dihydro-8-hydroxygambogic acid shows anticancer activity.

S-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. S-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC₅₀ values of 4.49 and 3.61 μM for K562/R and K562/S, respectively. S-30-Hydroxygambogic acid can be used for the research of cancer.

10α-Hydroxyepigambogic acid can be extracted from Garcinia hanburyi. 10α-Hydroxyepigambogic acid can be used in the research of tumors.

Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research.

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats.

3,8-Dihydroxy-2,4,6-trimethoxyxanthone is a trimethoxyxanthone, a natural product, can be isolated from the stems of Garcinia multiflora.

Isogambogenic acid is a natural product that can be isolated from Resina Garciniae. Isogambogenic acid has cytotoxicity to cancer cell lines with IC₅₀ values of 0.4327-5.942 μmol/L.

Garcinielliptone HD is a compound isolated from the heartwood of Garcinia subelliptica Merr. .

Albaspidin AA displays strong antibacterial activity against the vegetative form of Paenibacillus larvae (P. larvae) (MIC=220 μM).

Mbarraxanthone (1,3,7-Trihydroxy-4-prenylxanthone) is a prenylated trioxygenated xanthone. Mbarraxanthone exhibits inhibitory activity against Gram-positive and Gram-negative bacteria, and inhibits lipopolysaccharide-induced nitric oxide (NO) production in macrophages. Mbarraxanthone can be used in research on bacterial infections.

St John's Wort Extract is the extract of St John's Wort, with content of 0.3% Hypercins.

Butyl benzoate (Standard) is the analytical standard of Butyl benzoate (HY-W016599). This product is intended for research and analytical applications. Butyl benzoate (n-Butyl Benzoate) is an ester of an aromatic acid that can be used as a perfume ingredient.

Protohypericin is a compound that can be extracted from Hypericum perforatum. Protohypericin has low photocytotoxicity but can be efficiently photoconverted into Hypericin (HY-N0453) with high phototoxicity under visible light. Protohypericin can be used in cancer research.

Macurin is a xanthone that can be isolated from Garcinia lancilimba.

Garcinol (Standard) is the analytical standard of Garcinol. This product is intended for research and analytical applications. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively. Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity.

Parvifolixanthone A is a xanthone compound that can be isolated from Garcinia parvifolia. Parvifolixanthone A exhibits antioxidant activity with IC₅₀ of submicromolar level (0.18–0.38 μM).

Isomorellinol is a xanthone with an anticancer potency. Isomorellinol induces apoptosis in cholangiocarcinoma cells. Isomorellinol increases the Bax/Bcl-2 protein expression ratio and decreases survivin protein expression in cholangiocarcinoma cells.

Parvifolixanthone B is a Xanthones product that can be isolated from the twigs of Garcinia parvifolia..

2,5-Dihydroxyxanthone is a Xanthones product that can be isolated from the stem barks of Garcinia tetrandra.