Piperaceae Extract

Pyrroside B (compound 1) can be isolated from the methanol (MeOH) extract of the aerial part of Piper elongatum VAHL. Pyrroside B has antioxidative activity.

Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC₅₀ of 18.1 μg/mL.

3-chloro-4-hydroxy-2-piperidone can be isolated fromP.hancei.

Dehydropipernonaline (Compound 24) is an amide compound. Dehydropipernonaline shows considerable cytotoxicity to L5178Y mouse lymphoma cells (IC₅₀8.9μM). Dehydropipernonaline can be used for screening antifungal and cytotoxicity .

Piperundecalidine is an amide alkaloids that can be purified from Piper longum L. Piperundecalidine shows various biological properties, such as anti-inammatory, analgesic, anti-amoebic, anti-depressant, hepatoprotective,etc..

Guineesine can be isolated from Piper longum L.

Kadsurenin A is a bioactive Lignan from the genus Piper L.

cis-Burchellin is a bioactive neolignan with anti-allergic activity. cis-Burchellin inhibits IL-2 production in Jurkat T-cells.

Burchellin is a neolignan that can inhibit Trypanosoma cruzi.

Kadsurin A is a new lignan can be isolated from Piper futokadsura. Kadsurin A is a platelet activating factor (PAF) receptor antagonist that weakly inhibits the binding of PAF to its receptor.

(-)-Galbelgin is a lignan diastereoisomer. (-)-Galbelgin can be isolated from Piper kadsura.

Hancinone is a lignanoid, which can be isolated from Piper pleiocarpum Chang.

Piperlotine D is an antiplatelet aggregation agent. Piperlotine D can be extracted from Piper lolot with antiplatelet aggregation activity. Piperlotine D inhibits arachidonic acid-induced platelet aggregation with an IC₅₀ of 43.4 μg/mL.

Hancinone C (compound 2) is a natural product that can be found in Piper hancei.

Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani.

Nervogenic acid is an aromatic compound that can be isolated from Piper elongatum VAHL. Nervogenic acid has antibacterial activities and antioxidative effects.

Isodihydrofutoquinol B (compound 9), an active compound, can be isolated from the stems of Piper kadsura (Choisy) Ohwi. Isodihydrofutoquinol B has A neuroprotective effect on Aβ25-35-induced PC12 cell damage with E₅₀ values of 3.06-29.3μM.

Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC₅₀ value of 27 µM for W2 strain of Plasmodium falciparum.

Futoamide is an active compound. Futoamide can be isolated from Piper futokadzura SIEB. et ZUCC.

Kusunokinin ((-)-Kusunokinin) is a nature product that could be isolated form P. nigrum. Kusunokinin has anticancer activity. Kusunokinin arrests cell cycle at G2/M phase and induce apoptosis.