20(R)-Protopanaxatriol
Based on 1 publication(s) in Google Scholar
20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh.
For research use only. We do not sell to patients.
- Purity: 99.70%
- CAS No.: 1453-93-6
- Formula: C30H52O4
- Molecular Weight:476.73
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) 20(R)-Protopanaxatriol
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
58.29 μM
Compound: 8
|
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 26420067] |
| HL-60 | IC50 |
28.68 μM
Compound: 8
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 26420067] |
20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1453-93-6
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Appearance Solid
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Molecular Weight 476.73
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Formula C30H52O4
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Color White to off-white
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SMILES
C[C@]([C@@](C[C@H]1O)([H])[C@]([C@]2([H])C3(C)C)(CC[C@@H]3O)C)(C[C@@H]2O)[C@@]([C@@]1([H])[C@@]4([H])[C@](C)(O)CC/C=C(C)\C)(CC4)C
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Synonyms
20(R)-APPT
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Pharmacol Sin
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1. [Abstract]2025 Jun 23. PMID: 40550962
Solvent & Solubility
DMSO : ≥ 32 mg/mL (67.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0976 mL | 10.4881 mL | 20.9762 mL | 52.4406 mL |
| 5 mM | 0.4195 mL | 2.0976 mL | 4.1952 mL | 10.4881 mL | |
| 10 mM | 0.2098 mL | 1.0488 mL | 2.0976 mL | 5.2441 mL | |
| 15 mM | 0.1398 mL | 0.6992 mL | 1.3984 mL | 3.4960 mL | |
| 20 mM | 0.1049 mL | 0.5244 mL | 1.0488 mL | 2.6220 mL | |
| 25 mM | 0.0839 mL | 0.4195 mL | 0.8390 mL | 2.0976 mL | |
| 30 mM | 0.0699 mL | 0.3496 mL | 0.6992 mL | 1.7480 mL | |
| 40 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3110 mL | |
| 50 mM | 0.0420 mL | 0.2098 mL | 0.4195 mL | 1.0488 mL | |
| 60 mM | 0.0350 mL | 0.1748 mL | 0.3496 mL | 0.8740 mL |