1. Endocrinology

Endocrinology

Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-U00367
    (4E)-SUN9221 222318-55-0 98%
    (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
    (4E)-SUN9221
  • HY-U00371
    AR-08 226081-74-9 98%
    AR-​08 is an agonist of α2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD).
    AR-08
  • HY-U00375
    Gastrin/CCK antagonist 1 162271-52-5 98%
    Gastrin/CCK antagonist 1 is an antagonist of gastrin/CCK, used for the research of gastrointestinal disorders.
    Gastrin/CCK antagonist 1
  • HY-U00386
    Bometolol Hydrochloride 65023-16-7 98%
    Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
    Bometolol Hydrochloride
  • HY-U00387
    CCK-A receptor inhibitor 1 137004-80-9 98%
    CCK-A receptor inhibitor 1 is a cholecystokinin A (CCK-A) receptor inhibitor with a binging IC50 of 340 nM.
    CCK-A receptor inhibitor 1
  • HY-U00391
    β3-AR agonist 2 340757-05-3 98%
    β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM.
    β3-AR agonist 2
  • HY-U00392
    Tachykinin angatonist 1 178310-77-5 98%
    Tachykinin angatonist 1 is a neurokinin receptor antagonist extracted from patent US5968923, compound example 32.
    Tachykinin angatonist 1
  • HY-U00396
    MC-4R Agonist 1 455957-28-5 98%
    MC-4R Agonist 1 is an agonist of human melanocortin-4 receptor (MC-4R), used in the research of obesity, diabetes, and sexual dysfunction.
    MC-4R Agonist 1
  • HY-U00399
    Fiduxosin 208993-54-8 98%
    Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.
    Fiduxosin
  • HY-U00402
    Fenmetozole Tosylate 83474-08-2 98%
    Fenmetozole Tosylate is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor, and acts as an antidepressant agent.
    Fenmetozole Tosylate
  • HY-U00404
    Phentolamine Analogue 1 47142-51-8 98%
    Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
    Phentolamine Analogue 1
Cat. No. Product Name / Synonyms Application Reactivity