Endocrinology

MRE-269 (Standard) is the analytical standard of MRE-269. This product is intended for research and analytical applications. MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist.

Dapiprazole (hydrochloride) (Standard) is the analytical standard of Dapiprazole (hydrochloride). This product is intended for research and analytical applications. Dapiprazole hydrochloride is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole hydrochloride suppresses the opioid withdrawal symptoms. Dapiprazole hydrochloride is also used as eye drops for reversing mydriasis.

L 888607 (Standard) is the analytical standard of L 888607 (HY-111271). This product is intended for research and analytical applications. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a K_i value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite.

11-Dodecyn-1-ol (Standard) is the analytical standard of 11-Dodecyn-1-ol (HY-W007273). This product is intended for research and analytical applications. 11-Dodecyn-1-ol is a synthetic intermediate of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate for Thaumetopoea processionea.

KW-8232 (Standard) is the analytical standard of KW-8232 (HY-100304A). This product is intended for research and analytical applications. KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.

YM511 (Standard) is the analytical standard of YM511 (HY-105184). This product is intended for research and analytical applications. YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC₅₀s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.

HT-2157 (Standard) is the analytical standard of HT-2157 (HY-100717). This product is intended for research and analytical applications. HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).

(9E)-Tetradecen-1-ol is a pheromone that has no significant sexual attraction when used alone and can be secreted from the abdomen of the female Bertha armyworm moth (Mamestra configurata (Walker)). Isolate in tip extract to get in isolate. Another pheromone (Z)-11-hexadecen-1-ol was also isolated at the same time. Only when the two pheromones are mixed do they show male attraction (the ratio of C16:C14 in the mixture is about 19:1). optimal).

Atenolol-d₆ ((RS)-Atenolol-d₆) is deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a K_i of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris.

3β hydroxy Tibolone-d₅ is deuterium labeled Tibolone. Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.

T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC₅₀ of 0.2 nM.

Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.

Neurokinin A (4-10) is a tachykinin NK₂ receptor agonist.

Trecadrine is a β3-adrenergic agonist.

Physalaemin, a non-mammalian tachykinin, binds selectively to neurokinin-1 (NK1) receptor with high affinity.

MEN11467 is a selective and orally- effective peptidomimetic tachykinin NK₁ receptor antagonist.

KAT681 is a liver-selective thyromimetic.

KP136 (AL136) is an orally effective antiallergic agent. The IC₅₀ is 76.1 μg/mL for histamine release and 63 ug/mL for degranulation.

Falintolol, (Z)-, a new β-adrenergic antagonist, is characterized by the presence of an oxime function.