Infection

N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger.

ZX-2401 (Compound 98a) is a 1,3,5-Triazine-based analogue of Purine (HY-34431). ZX-2401 has a significant antiviral activity against viruses of the Flaviviridae family, such as West Nile Virus (WNV), Hepatitis C (HCV), Yellow Fever Virus (YFV), Dengue Virus (DV), Bovine Viral Diarrhea Virus (BVDV) and Banzi Virus (BV) with EC₉₀s of 0.6-10 μg/mL. ZX-2401 significantly reduces virus production with an EC₉₀ of 3.3 mg/mL. ZX-2401 can be used for influenza infections research.

Neutramycin is a neutral macrolide antibiotic with a complex composition and classification.

Pinselin is a nitrogen-containing heterocyclic antibiotic. Pinselin has anti-yeast activity.

Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle.

GP-1681 is a Beraprost sodium (HY-13569A) analogue. GP-1681 can be used in the research of influenza A H5N1 infection.

Tolindate is a potent PXR agonist with an EC₅₀ value of 8.3 μM. Tolindate shows antifungal activity.

Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4 and exhibits excellent antifungal activity against B. cinerea with EC₅₀ value of 0.56 μg/mL.

ZBP1 PROTAC-1 is a PROTAC degrader targeting ZBP1, with a DC₅₀ of 81.52 nM. ZBP1 PROTAC-1 uses a DNA aptamer to specifically bind ZBP1, recruits the VHL E3 ubiquitin ligase, and induces ZBP1 degradation via the ubiquitin-proteasome pathway. ZBP1 PROTAC-1 can partially restore the viability of H1N1-infected cells. ZBP1 PROTAC-1 can be used in studies related to viral pneumonia and influenza A H1N1 virus infection.

SARS-CoV-2-IN-111 (compound 77) is a potent SARS-CoV-2 inhibitor with an IC₅₀ of 0.67 μM. SARS-CoV-2-IN-111 significantly reduces SARS-CoV-2 within Vero cells.

Dodemorph is a fungicide. Dodemorph exerts antifungal effects by inhibiting ergosterol biosynthesis. Dodemorph can be used in studies related to fungal mildew in rose cultivation.

Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC₅₀ of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.

Melibionic acid is a galactose derivative and a ganglioside GD_1b inhibitor. Melibionic acid inhibits heat-labile enterotoxin with an IC₅₀ of 7 mM.

CPO 4 is a DNA-targeting antibacterial agent. CPO 4 intercalates into DNA to form a CPO 4-DNA complex, thereby blocking DNA replication. CPO 4 disrupts the metabolic activity of bacteria. CPO 4 induces intracellular protein leakage in bacteria. CPO 4 can be used for the research of drug-resistant bacterial infections.

Robenidine hydrochloride (Standard) is the analytical standard of Robenidine hydrochloride. This product is intended for research and analytical applications. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.

DHFR-IN-12 (Compound 5c) is a DHFR inhibitor which has good antibacterial activity.

Cynarin (Standard) is the analytical standard of Cynarin. This product is intended for research and analytical applications. Cynarin is an antichoke agent with a variety of biological activities including antioxidant, antihistamic and antiviral activities.

Pyrromycin is an antibiotic against Gram-positive bacteria.

Thiethylperazine-d₃ is the deuterium labeled Thiethylperazinee (HY-B1794). Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects.

Pradimicin B is an antibiotic. Pradimicin B has strong antifungal and yeast activity.